RNA editing alterations define manifestation of prion diseases

Prion diseases are fatal neurodegenerative disorders caused by misfolding of the normal prion protein into an infectious cellular pathogen. Clinically characterized by rapidly progressive dementia and accounting for 85% of human prion disease cases, sporadic Creutzfeldt–Jakob disease (sCJD) is the p...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kanata, Eirini, Llorens, Franc, Dafou, Dimitra, Dimitriadis, Athanasios, Thüne, Katrin, Xanthopoulos, Konstantinos, Bekas, Nikolaos, Espinosa, Juan Carlos, Schmitz, Matthias, Marín-Moreno, Alba, Capece, Vincenzo, Shormoni, Orr, Andréoletti, Olivier, Bonn, Stefan, Torres, Juan María, Ferrer, Isidre, Zerr, Inga, Sklaviadis, Theodoros
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765247/
https://ncbi.nlm.nih.gov/pubmed/31492812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1803521116
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