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Complex dynamics under tension in a high-efficiency frameshift stimulatory structure

Specific structures in mRNA can stimulate programmed ribosomal frameshifting (PRF). PRF efficiency can vary enormously between different stimulatory structures, but the features that lead to efficient PRF stimulation remain uncertain. To address this question, we studied the structural dynamics of t...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Halma, Matthew T. J., Ritchie, Dustin B., Cappellano, Tonia R., Neupane, Krishna, Woodside, Michael T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765238/
https://ncbi.nlm.nih.gov/pubmed/31409714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1905258116
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