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Programmed −1 frameshifting efficiency correlates with RNA pseudoknot conformational plasticity, not resistance to mechanical unfolding

Programmed −1 frameshifting, whereby the reading frame of a ribosome on messenger RNA is shifted in order to generate an alternate gene product, is often triggered by a pseudoknot structure in the mRNA in combination with an upstream slippery sequence. The efficiency of frameshifting varies widely f...

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מידע ביבליוגרפי
Main Authors: Ritchie, Dustin B., Foster, Daniel A. N., Woodside, Michael T.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479558/
https://ncbi.nlm.nih.gov/pubmed/22988073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204114109
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