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Complex dynamics under tension in a high-efficiency frameshift stimulatory structure

Specific structures in mRNA can stimulate programmed ribosomal frameshifting (PRF). PRF efficiency can vary enormously between different stimulatory structures, but the features that lead to efficient PRF stimulation remain uncertain. To address this question, we studied the structural dynamics of t...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Halma, Matthew T. J., Ritchie, Dustin B., Cappellano, Tonia R., Neupane, Krishna, Woodside, Michael T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765238/
https://ncbi.nlm.nih.gov/pubmed/31409714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1905258116
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