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Insoluble Aβ overexpression in an App knock-in mouse model alters microstructure and gamma oscillations in the prefrontal cortex, affecting anxiety-related behaviours
We studied a new amyloid-beta precursor protein (App) knock-in mouse model of Alzheimer's disease (App(NL-G-F)), containing the Swedish KM670/671NL mutation, the Iberian I716F mutation and the Artic E693G mutation, which generates elevated levels of amyloid beta (Aβ)(40) and Aβ(42) without the...
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| 出版年: | Dis Model Mech |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Company of Biologists Ltd
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6765200/ https://ncbi.nlm.nih.gov/pubmed/31439589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.040550 |
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