Insights into telomeric G-quadruplex DNA recognition by HMGB1 protein

HMGB1 is a ubiquitous non-histone protein, which biological effects depend on its expression and subcellular location. Inside the nucleus, HMGB1 is engaged in many DNA events such as DNA repair, transcription and telomere maintenance. HMGB1 has been reported to bind preferentially to bent DNA as wel...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Amato, Jussara, Cerofolini, Linda, Brancaccio, Diego, Giuntini, Stefano, Iaccarino, Nunzia, Zizza, Pasquale, Iachettini, Sara, Biroccio, Annamaria, Novellino, Ettore, Rosato, Antonio, Fragai, Marco, Luchinat, Claudio, Randazzo, Antonio, Pagano, Bruno
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Structural Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765150/
https://ncbi.nlm.nih.gov/pubmed/31504744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz727
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