Common G-Quadruplex Binding Agents Found to Interact With i-Motif-Forming DNA: Unexpected Multi-Target-Directed Compounds

G-quadruplex (G4) and i-motif (iM) are four-stranded non-canonical nucleic acid structural arrangements. Recent evidences suggest that these DNA structures exist in living cells and could be involved in several cancer-related processes, thus representing an attractive target for anticancer drug disc...

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Bibliografische gegevens
Gepubliceerd in:Front Chem
Hoofdauteurs: Pagano, Alessia, Iaccarino, Nunzia, Abdelhamid, Mahmoud A. S., Brancaccio, Diego, Garzarella, Emanuele U., Di Porzio, Anna, Novellino, Ettore, Waller, Zoë A. E., Pagano, Bruno, Amato, Jussara, Randazzo, Antonio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2018
Onderwerpen:
Chemistry
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6066642/
https://ncbi.nlm.nih.gov/pubmed/30137743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00281
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