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Dedifferentiation process driven by radiotherapy-induced HMGB1/TLR2/YAP/HIF-1α signaling enhances pancreatic cancer stemness
Differentiated cancer cells reacquiring stem cell traits following radiotherapy may enrich cancer stem cells and accelerate tumor recurrence and metastasis. We are interested in the mechanistic role of dying cells-derived HMGB1 in CD133(−) pancreatic cancer cells dedifferentiation following radiothe...
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| Publicado no: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6763460/ https://ncbi.nlm.nih.gov/pubmed/31558702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1956-8 |
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