Dedifferentiation process driven by radiotherapy-induced HMGB1/TLR2/YAP/HIF-1α signaling enhances pancreatic cancer stemness

Differentiated cancer cells reacquiring stem cell traits following radiotherapy may enrich cancer stem cells and accelerate tumor recurrence and metastasis. We are interested in the mechanistic role of dying cells-derived HMGB1 in CD133(−) pancreatic cancer cells dedifferentiation following radiothe...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cell Death Dis
Hlavní autoři: Zhang, Lirong, Shi, Hui, Chen, Hongbo, Gong, Aihua, Liu, Yanfang, Song, Lian, Xu, Xuewen, You, Tao, Fan, Xin, Wang, Dongqing, Cheng, Fang, Zhu, Haitao
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763460/
https://ncbi.nlm.nih.gov/pubmed/31558702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1956-8
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky