Radiotherapy-induced cell death activates paracrine HMGB1-TLR2 signaling and accelerates pancreatic carcinoma metastasis

BACKGROUND: Dying cells after irradiation could promote the repopulation of surviving cancer cells leading to tumor recurrence. We aim to define the role of dying cells in promoting pancreatic cancer cells metastasis following radiotherapy. METHODS: Using the transwell system as the in vitro co-cult...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Chen, Xuelian, Zhang, Lirong, Jiang, Yujie, Song, Lian, Liu, Yanfang, Cheng, Fang, Fan, Xin, Cao, Xiongfeng, Gong, Aihua, Wang, Dongqing, Zhu, Haitao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883315/
https://ncbi.nlm.nih.gov/pubmed/29615080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0726-2
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