Radiotherapy-induced cell death activates paracrine HMGB1-TLR2 signaling and accelerates pancreatic carcinoma metastasis

BACKGROUND: Dying cells after irradiation could promote the repopulation of surviving cancer cells leading to tumor recurrence. We aim to define the role of dying cells in promoting pancreatic cancer cells metastasis following radiotherapy. METHODS: Using the transwell system as the in vitro co-cult...

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Publicat a:J Exp Clin Cancer Res
Autors principals: Chen, Xuelian, Zhang, Lirong, Jiang, Yujie, Song, Lian, Liu, Yanfang, Cheng, Fang, Fan, Xin, Cao, Xiongfeng, Gong, Aihua, Wang, Dongqing, Zhu, Haitao
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883315/
https://ncbi.nlm.nih.gov/pubmed/29615080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0726-2
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