IL-1β dominates the promucin secretory cytokine profile in cystic fibrosis

Cystic fibrosis (CF) lung disease is characterized by early and persistent mucus accumulation and neutrophilic inflammation in the distal airways. Identification of the factors in CF mucopurulent secretions that perpetuate CF mucoinflammation may provide strategies for novel CF pharmacotherapies. We...

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Publicado no:J Clin Invest
Main Authors: Chen, Gang, Sun, Ling, Kato, Takafumi, Okuda, Kenichi, Martino, Mary B., Abzhanova, Aiman, Lin, Jennifer M., Gilmore, Rodney C., Batson, Bethany D., O’Neal, Yvonne K., Volmer, Allison S., Dang, Hong, Deng, Yangmei, Randell, Scott H., Button, Brian, Livraghi-Butrico, Alessandra, Kesimer, Mehmet, Ribeiro, Carla M.P., O’Neal, Wanda K., Boucher, Richard C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763234/
https://ncbi.nlm.nih.gov/pubmed/31524632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI125669
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