XBP1S Regulates MUC5B in a Promoter Variant–Dependent Pathway in Idiopathic Pulmonary Fibrosis Airway Epithelia

Rationale: The goal was to connect elements of idiopathic pulmonary fibrosis (IPF) pathogenesis, including chronic endoplasmic reticulum stress in respiratory epithelia associated with injury/inflammation and remodeling, distal airway mucus obstruction and honeycomb cyst formation with accumulation...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Chen, Gang, Ribeiro, Carla M. P., Sun, Ling, Okuda, Kenichi, Kato, Takafumi, Gilmore, Rodney C., Martino, Mary B., Dang, Hong, Abzhanova, Aiman, Lin, Jennifer M., Hull-Ryde, Emily A., Volmer, Allison S., Randell, Scott H., Livraghi-Butrico, Alessandra, Deng, Yingfeng, Scherer, Philipp E., Stripp, Barry R., O’Neal, Wanda K., Boucher, Richard C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635783/
https://ncbi.nlm.nih.gov/pubmed/30973754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201810-1972OC
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