Caspase 3 Deficiency Rescues Peripheral Nervous System Defect in Retinoblastoma Nullizygous Mice

The retinoblastoma tumor suppressor protein, pRb, is a key regulator of cell cycle and has been implicated in the terminal differentiation of neuronal cells. Mice nullizygous for pRb die by embryonic day 14.5 from hematopoietic and neurological defects attributed to failed differentiation (Clarke et...

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Publicado no:J Neurosci
Main Authors: Simpson, Matthew T. W., MacLaurin, Jason G., Xu, Daigen, Ferguson, Kerry L., Vanderluit, Jacqueline L., Davoli, Maria A., Roy, Sophie, Nicholson, Donald W., Robertson, George S., Park, David S., Slack, Ruth S.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2001
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762980/
https://ncbi.nlm.nih.gov/pubmed/11549719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-18-07089.2001
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