The Retinoblastoma family member p107 regulates the rate of progenitor commitment to a neuronal fate

The Retinoblastoma protein p107 regulates the neural precursor pool in both the developing and adult brain. As p107-deficient mice exhibit enhanced levels of Hes1, we questioned whether p107 regulates neural precursor self-renewal through the repression of Hes1. p107 represses transcription at the H...

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Библиографические подробности
Главные авторы: Vanderluit, Jacqueline L., Wylie, Crystal A., McClellan, Kelly A., Ghanem, Noel, Fortin, Andre, Callaghan, Steve, MacLaurin, Jason G., Park, David S., Slack, Ruth S.
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2007
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Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064429/
https://ncbi.nlm.nih.gov/pubmed/17591923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200703176
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