Pronociceptive Actions of Dynorphin Maintain Chronic Neuropathic Pain

Whereas tissue injury increases spinal dynorphin expression, the functional relevance of this upregulation to persistent pain is unknown. Here, mice lacking the prodynorphin gene were studied for sensitivity to non-noxious and noxious stimuli, before and after induction of experimental neuropathic p...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Wang, Zaijie, Gardell, Luis R., Ossipov, Michael H., Vanderah, Todd W., Brennan, Miles B., Hochgeschwender, Ute, Hruby, Victor J., Malan, T. Phil, Lai, Josephine, Porreca, Frank
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2001
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ARTICLE
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762963/
https://ncbi.nlm.nih.gov/pubmed/11222667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-05-01779.2001
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