Pronociceptive Actions of Dynorphin Maintain Chronic Neuropathic Pain

Whereas tissue injury increases spinal dynorphin expression, the functional relevance of this upregulation to persistent pain is unknown. Here, mice lacking the prodynorphin gene were studied for sensitivity to non-noxious and noxious stimuli, before and after induction of experimental neuropathic p...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Wang, Zaijie, Gardell, Luis R., Ossipov, Michael H., Vanderah, Todd W., Brennan, Miles B., Hochgeschwender, Ute, Hruby, Victor J., Malan, T. Phil, Lai, Josephine, Porreca, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2001
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762963/
https://ncbi.nlm.nih.gov/pubmed/11222667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-05-01779.2001
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