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Rapamycin and Alzheimer’s disease: Time for a clinical trial?
The drug rapamycin has beneficial effects in a number of animal models of neurodegeneration and aging including mouse models of Alzheimer’s disease. Despite its compelling preclinical record, no clinical trials have tested rapamycin or other mTOR inhibitors in patients with Alzheimer’s disease. We a...
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| Veröffentlicht in: | Sci Transl Med |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6762017/ https://ncbi.nlm.nih.gov/pubmed/30674654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aar4289 |
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