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Rapamycin and Alzheimer’s disease: Time for a clinical trial?
The drug rapamycin has beneficial effects in a number of animal models of neurodegeneration and aging including mouse models of Alzheimer’s disease. Despite its compelling preclinical record, no clinical trials have tested rapamycin or other mTOR inhibitors in patients with Alzheimer’s disease. We a...
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| Publicado en: | Sci Transl Med |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6762017/ https://ncbi.nlm.nih.gov/pubmed/30674654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aar4289 |
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