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Rapamycin and Alzheimer’s disease: Time for a clinical trial?

The drug rapamycin has beneficial effects in a number of animal models of neurodegeneration and aging including mouse models of Alzheimer’s disease. Despite its compelling preclinical record, no clinical trials have tested rapamycin or other mTOR inhibitors in patients with Alzheimer’s disease. We a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Transl Med
Egile Nagusiak: Kaeberlein, Matt, Galvan, Veronica
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762017/
https://ncbi.nlm.nih.gov/pubmed/30674654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aar4289
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