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CENP-A Ubiquitylation Is Indispensable to Cell Viability
CENP-A is a centromere-specific histone H3 variant that epigenetically determines centromere identity, but how CENP-A is deposited at the centromere remains obscure. We previously reported that CENP-A K124 ubiquitylation, mediated by the CUL4A-RBX1-COPS8 complex, is essential for CENP-A deposition a...
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| Publicado no: | Dev Cell |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6761987/ https://ncbi.nlm.nih.gov/pubmed/31550462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.07.015 |
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