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CENP-A K124 Ubiquitylation Is Required for CENP-A Deposition at the Centromere

CENP-A is a centromere-specific histone H3 variant that epigenetically determines centromere identity to ensure kinetochore assembly and proper chromo-some segregation, but the precise mechanism of its specific localization within centromeric heterochromatin remains obscure. We have discovered that...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Niikura, Yohei, Kitagawa, Risa, Ogi, Hiroo, Abdulle, Rashid, Pagala, Vishwajeeth, Kitagawa, Katsumi
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374629/
https://ncbi.nlm.nih.gov/pubmed/25727006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.01.024
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