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SGT1-HSP90 complex is required for CENP-A deposition at centromeres

The centromere plays an essential role in accurate chromosome segregation, and defects in its function lead to aneuploidy and thus cancer. The centromere-specific histone H3 variant CENP-A is proposed to be the epigenetic mark of the centromere, as active centromeres require CENP-A–containing nucleo...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Niikura, Yohei, Kitagawa, Risa, Ogi, Hiroo, Kitagawa, Katsumi
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602426/
https://ncbi.nlm.nih.gov/pubmed/28816574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1325039
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