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Pyrrolomycins Are Potent Natural Protonophores

The escalating burden of antibiotic drug resistance necessitates research into novel classes of antibiotics and their mechanism of action. Pyrrolomycins are a family of potent natural product antibiotics with nanomolar activity against Gram-positive bacteria, yet with an elusive mechanism of action....

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Valderrama, Katherine, Pradel, Elizabeth, Firsov, Alexander M., Drobecq, Hervé, Bauderlique-le Roy, Hélène, Villemagne, Baptiste, Antonenko, Yuri N., Hartkoorn, Ruben Christiaan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761498/
https://ncbi.nlm.nih.gov/pubmed/31405863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01450-19
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