Posaconazole Is a Potent Inhibitor of Sterol 14α-Demethylation in Yeasts and Molds

Posaconazole (POS; SCH 56592) is a novel triazole that is active against a wide variety of fungi, including fluconazole-resistant Candida albicans isolates and fungi that are inherently less susceptible to approved azoles, such as Candida glabrata. In this study, we compared the effects of POS, itra...

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Detalhes bibliográficos
Main Authors: Munayyer, Hanan K., Mann, Paul A., Chau, Andrew S., Yarosh-Tomaine, Taisa, Greene, Jonathan R., Hare, Roberta S., Heimark, Larry, Palermo, Robert E., Loebenberg, David, McNicholas, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC521889/
https://ncbi.nlm.nih.gov/pubmed/15388421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.10.3690-3696.2004
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