NitroSynapsin for the treatment of neurological manifestations of Tuberous Sclerosis Complex in a rodent model

Tuberous sclerosis (TSC) is an autosomal dominant disorder caused by heterozygous mutations in the TSC1 or TSC2 gene. TSC is often associated with neurological, cognitive, and behavioral deficits. TSC patients also express co-morbidity with anxiety and mood disorders. The mechanism of pathogenesis i...

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Dettagli Bibliografici
Pubblicato in:Neurobiol Dis
Autori principali: Okamoto, Shu-ichi, Prikhodko, Olga, Pina-Crespo, Juan, Adame, Anthony, McKercher, Scott R., Brill, Laurence M., Nakanishi, Nobuki, Oh, Chang-ki, Nakamura, Tomohiro, Masliah, Eliezer, Lipton, Stuart A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760869/
https://ncbi.nlm.nih.gov/pubmed/30928642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2019.03.029
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