NitroSynapsin for the treatment of neurological manifestations of Tuberous Sclerosis Complex in a rodent model

Tuberous sclerosis (TSC) is an autosomal dominant disorder caused by heterozygous mutations in the TSC1 or TSC2 gene. TSC is often associated with neurological, cognitive, and behavioral deficits. TSC patients also express co-morbidity with anxiety and mood disorders. The mechanism of pathogenesis i...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Okamoto, Shu-ichi, Prikhodko, Olga, Pina-Crespo, Juan, Adame, Anthony, McKercher, Scott R., Brill, Laurence M., Nakanishi, Nobuki, Oh, Chang-ki, Nakamura, Tomohiro, Masliah, Eliezer, Lipton, Stuart A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760869/
https://ncbi.nlm.nih.gov/pubmed/30928642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2019.03.029
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