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NitroSynapsin ameliorates hypersynchronous neural network activity in Alzheimer hiPSC models
Beginning at early stages, human Alzheimer’s disease (AD) brains manifest hyperexcitability, contributing to subsequent extensive synapse loss, which has been linked to cognitive dysfunction. No current therapy for AD is disease-modifying. Part of the problem with AD drug discovery is that transgeni...
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| Publicado no: | Mol Psychiatry |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7704704/ https://ncbi.nlm.nih.gov/pubmed/32467645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-020-0776-7 |
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