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Differential Effects of Pharmacologic and Genetic Modulation of NMDA Receptor Activity on HIV/gp120-Induced Neuronal Damage in an In Vivo Mouse Model

HIV-associated neurocognitive disorder (HAND) consists of motor and cognitive dysfunction in a relatively large percentage of patients with AIDS. Prior work has suggested that at least part of the neuronal and synaptic damage observed in HAND may occur due to excessive stimulation of NMDA-type gluta...

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Detalhes bibliográficos
Publicado no:J Mol Neurosci
Main Authors: Nakanishi, Nobuki, Kang, Yeon-Joo, Tu, Shichun, McKercher, Scott R., Masliah, Eliezer, Lipton, Stuart A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821006/
https://ncbi.nlm.nih.gov/pubmed/26374431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-015-0651-1
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