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Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis

HIV-1 glycoprotein gp120 induces injury and apoptosis in rodent and human neurons in vitro and in vivo and is therefore thought to contribute to HIV-associated dementia. In addition to CD4, different gp120 isolates bind to the α- or β-chemokine receptors CXCR4 and CCR5, respectively. These and other...

詳細記述

保存先:
書誌詳細
主要な著者: Kaul, Marcus, Lipton, Stuart A.
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 1999
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC22214/
https://ncbi.nlm.nih.gov/pubmed/10393974
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