Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis
HIV-1 glycoprotein gp120 induces injury and apoptosis in rodent and human neurons in vitro and in vivo and is therefore thought to contribute to HIV-associated dementia. In addition to CD4, different gp120 isolates bind to the α- or β-chemokine receptors CXCR4 and CCR5, respectively. These and other...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22214/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10393974/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.14.8212 |
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