Differential Effects of Synaptic and Extrasynaptic NMDA Receptors on Aβ-Induced Nitric Oxide Production in Cerebrocortical Neurons

Oligomerized amyloid-β (Aβ) peptide is thought to contribute to synaptic damage, resulting in dysfunctional neuronal networks in patients with Alzheimer's disease. It has been previously suggested that Aβ may be detrimental to neuronal health, at least in part, by triggering oxidative/nitrosati...

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Detalhes bibliográficos
Main Authors: Molokanova, Elena, Akhtar, Mohd Waseem, Sanz-Blasco, Sara, Tu, Shichun, Piña-Crespo, Juan C., McKercher, Scott R., Lipton, Stuart A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972726/
https://ncbi.nlm.nih.gov/pubmed/24695719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2907-13.2014
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