Modulation of NMDA Receptor Properties and Synaptic Transmission by the NR3A Subunit in Mouse Hippocampal and Cerebrocortical Neurons

Expression of the NR3A subunit with NR1/NR2 in Xenopus oocytes or mammalian cell lines leads to a reduction in N-methyl-D-aspartate (NMDA)-induced currents and decreased Mg(2+) sensitivity and Ca(2+) permeability compared with NR1/NR2 receptors. Consistent with these findings, neurons from NR3A knoc...

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Publicat a:J Neurophysiol
Autors principals: Tong, Gary, Takahashi, Hiroto, Tu, Shichun, Shin, Yeonsook, Talantova, Maria, Zago, Wagner, Xia, Peng, Nie, Zhiguo, Goetz, Thomas, Zhang, Dongxian, Lipton, Stuart A., Nakanishi, Nobuki
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586267/
https://ncbi.nlm.nih.gov/pubmed/18003876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.01044.2006
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