Telomere dysfunction impairs epidermal stem cell specification and differentiation by disrupting BMP/pSmad/P63 signaling

Telomere shortening is associated with aging and age-associated diseases. Additionally, telomere dysfunction resulting from telomerase gene mutation can lead to premature aging, such as apparent skin atrophy and hair loss. However, the molecular signaling linking telomere dysfunction to skin atrophy...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Liu, Na, Yin, Yu, Wang, Haiying, Zhou, Zhongcheng, Sheng, Xiaoyan, Fu, Haifeng, Guo, Renpeng, Wang, Hua, Yang, Jiao, Gong, Peng, Ning, Wen, Ju, Zhenyu, Liu, Yifei, Liu, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760834/
https://ncbi.nlm.nih.gov/pubmed/31518356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008368
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