Telomere dysfunction impairs epidermal stem cell specification and differentiation by disrupting BMP/pSmad/P63 signaling

Telomere shortening is associated with aging and age-associated diseases. Additionally, telomere dysfunction resulting from telomerase gene mutation can lead to premature aging, such as apparent skin atrophy and hair loss. However, the molecular signaling linking telomere dysfunction to skin atrophy...

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Udgivet i:PLoS Genet
Main Authors: Liu, Na, Yin, Yu, Wang, Haiying, Zhou, Zhongcheng, Sheng, Xiaoyan, Fu, Haifeng, Guo, Renpeng, Wang, Hua, Yang, Jiao, Gong, Peng, Ning, Wen, Ju, Zhenyu, Liu, Yifei, Liu, Lin
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6760834/
https://ncbi.nlm.nih.gov/pubmed/31518356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008368
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