Fascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments

The deregulation of the actin cytoskeleton has been extensively studied in metastatic dissemination. However, the post-dissemination role of the actin cytoskeleton dysregulation is poorly understood. Here, we report that fascin, an actin-bundling protein, promotes lung cancer metastatic colonization...

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Foilsithe in:Cell Rep
Main Authors: Lin, Shengchen, Huang, Chongbiao, Gunda, Venugopal, Sun, Jianwei, Chellappan, Srikumar P., Li, Zengxun, Izumi, Victoria, Fang, Bin, Koomen, John, Singh, Pankaj K., Hao, Jihui, Yang, Shengyu
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2019
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6759858/
https://ncbi.nlm.nih.gov/pubmed/31509745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.08.011
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