Monoubiquitination Inhibits the Actin Bundling Activity of Fascin

Fascin is an actin bundling protein that cross-links individual actin filaments into straight, compact, and stiff bundles, which are crucial for the formation of filopodia, stereocillia, and other finger-like membrane protrusions. The dysregulation of fascin has been implicated in cancer metastasis,...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Lin, Shengchen, Lu, Shuang, Mulaj, Mentor, Fang, Bin, Keeley, Tyler, Wan, Lixin, Hao, Jihui, Muschol, Martin, Sun, Jianwei, Yang, Shengyu
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207158/
https://ncbi.nlm.nih.gov/pubmed/27879315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.767640
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