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Mechanism of Actin Filament Bundling by Fascin

Fascin is the main actin filament bundling protein in filopodia. Because of the important role filopodia play in cell migration, fascin is emerging as a major target for cancer drug discovery. However, an understanding of the mechanism of bundle formation by fascin is critically lacking. Fascin cons...

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Detalhes bibliográficos
Main Authors: Jansen, Silvia, Collins, Agnieszka, Yang, Changsong, Rebowski, Grzegorz, Svitkina, Tatyana, Dominguez, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191048/
https://ncbi.nlm.nih.gov/pubmed/21685497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.251439
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