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The actin bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion
Fascin is an actin bundling protein involved in filopodia assembly and cancer invasion and metastasis of multiple epithelial cancer types. Fascin forms stable actin bundles with slow dissociation kinetics in vitro [1] and is regulated by phosphorylation of serine 39 by protein kinase C (PKC) [2]. Ca...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3163294/ https://ncbi.nlm.nih.gov/pubmed/20137952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2009.12.035 |
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