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The mitochondrial deoxyguanosine kinase is required for cancer cell stemness in lung adenocarcinoma

The mitochondrial deoxynucleotide triphosphate (dNTP) is maintained by the mitochondrial deoxynucleoside salvage pathway and dedicated for the mtDNA homeostasis, and the mitochondrial deoxyguanosine kinase (DGUOK) is a rate‐limiting enzyme in this pathway. Here, we investigated the role of the DGUOK...

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Dettagli Bibliografici
Pubblicato in:EMBO Mol Med
Autori principali: Lin, Shengchen, Huang, Chongbiao, Sun, Jianwei, Bollt, Oana, Wang, Xiuchao, Martine, Eric, Kang, Jiaxin, Taylor, Matthew D, Fang, Bin, Singh, Pankaj K, Koomen, John, Hao, Jihui, Yang, Shengyu
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895611/
https://ncbi.nlm.nih.gov/pubmed/31633874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201910849
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