FOXN3 controls liver glucose metabolism by regulating gluconeogenic substrate selection

The FOXN3 gene locus is associated with fasting blood glucose levels in non‐diabetic human population genetic studies. The blood glucose‐modifying variation within this gene regulates the abundance of both FOXN3 protein and transcript in primary human hepatocytes, with the hyperglycemia risk allele...

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Dades bibliogràfiques
Publicat a:Physiol Rep
Autors principals: Karanth, Santhosh, Chaurasia, Bhagirath, Bowman, Faith M., Tippetts, Trevor S., Holland, William L., Summers, Scott A., Schlegel, Amnon
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6759504/
https://ncbi.nlm.nih.gov/pubmed/31552709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14238
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