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FOXN3 hyperglycemic risk allele and insulin sensitivity in humans

OBJECTIVE: The rs8004664 variation within the FOXN3 gene is significantly and independently associated with fasting blood glucose in humans. We have previously shown that the hyperglycemia risk allele (A) increases FOXN3 expression in primary human hepatocytes; over-expression of human FOXN3 in zebr...

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Podrobná bibliografie
Vydáno v:BMJ Open Diabetes Res Care
Hlavní autoři: Erickson, Melissa L, Karanth, Santhosh, Ravussin, Eric, Schlegel, Amnon
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731827/
https://ncbi.nlm.nih.gov/pubmed/31543974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjdrc-2019-000688
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