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FOXN3 hyperglycemic risk allele and insulin sensitivity in humans
OBJECTIVE: The rs8004664 variation within the FOXN3 gene is significantly and independently associated with fasting blood glucose in humans. We have previously shown that the hyperglycemia risk allele (A) increases FOXN3 expression in primary human hepatocytes; over-expression of human FOXN3 in zebr...
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Publié dans: | BMJ Open Diabetes Res Care |
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Auteurs principaux: | , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
BMJ Publishing Group
2019
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6731827/ https://ncbi.nlm.nih.gov/pubmed/31543974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjdrc-2019-000688 |
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