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FOXN3 controls liver glucose metabolism by regulating gluconeogenic substrate selection

The FOXN3 gene locus is associated with fasting blood glucose levels in non‐diabetic human population genetic studies. The blood glucose‐modifying variation within this gene regulates the abundance of both FOXN3 protein and transcript in primary human hepatocytes, with the hyperglycemia risk allele...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Karanth, Santhosh, Chaurasia, Bhagirath, Bowman, Faith M., Tippetts, Trevor S., Holland, William L., Summers, Scott A., Schlegel, Amnon
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6759504/
https://ncbi.nlm.nih.gov/pubmed/31552709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14238
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