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FOXN3 controls liver glucose metabolism by regulating gluconeogenic substrate selection

The FOXN3 gene locus is associated with fasting blood glucose levels in non‐diabetic human population genetic studies. The blood glucose‐modifying variation within this gene regulates the abundance of both FOXN3 protein and transcript in primary human hepatocytes, with the hyperglycemia risk allele...

詳細記述

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書誌詳細
出版年:Physiol Rep
主要な著者: Karanth, Santhosh, Chaurasia, Bhagirath, Bowman, Faith M., Tippetts, Trevor S., Holland, William L., Summers, Scott A., Schlegel, Amnon
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6759504/
https://ncbi.nlm.nih.gov/pubmed/31552709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14238
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