Corticostriatopallidal Neuroprotection by Adenovirus-Mediated Ciliary Neurotrophic Factor Gene Transfer in a Rat Model of Progressive Striatal Degeneration

Ciliary neurotrophic factor (CNTF) is a potent protective factor for striatal neurons in animal models of Huntington's disease (HD). Clinical application of this potential therapeutic still requires the design and optimization of delivery systems. In the case of HD, spatial spread in the vast v...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Mittoux, Vincent, Ouary, Stéphane, Monville, Christelle, Lisovoski, Fabrice, Poyot, Thomas, Condé, Françoise, Escartin, Carole, Robichon, Régine, Brouillet, Emmanuel, Peschanski, Marc, Hantraye, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2002
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758779/
https://ncbi.nlm.nih.gov/pubmed/12040055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-11-04478.2002
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