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Ciliary Neurotrophic Factor Protects Striatal Neurons against Excitotoxicity by Enhancing Glial Glutamate Uptake

Ciliary neurotrophic factor (CNTF) is a potent neuroprotective cytokine in different animal models of glutamate-induced excitotoxicity, although its action mechanisms are still poorly characterized. We tested the hypothesis that an increased function of glial glutamate transporters (GTs) could under...

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Detalhes bibliográficos
Main Authors: Beurrier, Corinne, Faideau, Mathilde, Bennouar, Khaled-Ezaheir, Escartin, Carole, Kerkerian-Le Goff, Lydia, Bonvento, Gilles, Gubellini, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798716/
https://ncbi.nlm.nih.gov/pubmed/20062544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008550
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