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Endoplasmic Reticulum Stress and the Unfolded Protein Response in Cellular Models of Parkinson's Disease

6-Hydroxydopamine, 1-methyl-4-phenyl-pyridinium (MPP(+)), and rotenone cause the death of dopaminergic neurons in vitro and in vivo and are widely used to model Parkinson's disease. To identify regulated genes in such models, we performed serial analysis of gene expression on neuronal PC12 cell...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Ryu, Elizabeth J., Harding, Heather P., Angelastro, James M., Vitolo, Ottavio V., Ron, David, Greene, Lloyd A.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758450/
https://ncbi.nlm.nih.gov/pubmed/12486162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-24-10690.2002
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