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Massively parallel RNA device engineering in mammalian cells with RNA-Seq

Synthetic RNA-based genetic devices dynamically control a wide range of gene-regulatory processes across diverse cell types. However, the limited throughput of quantitative assays in mammalian cells has hindered fast iteration and interrogation of sequence space needed to identify new RNA devices. H...

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Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Xiang, Joy S., Kaplan, Matias, Dykstra, Peter, Hinks, Michaela, McKeague, Maureen, Smolke, Christina D.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757056/
https://ncbi.nlm.nih.gov/pubmed/31548547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12334-y
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