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In Vitro Screening and in Silico Modeling of RNA-Based Gene Expression Control

Molecular tools for controlling gene expression are essential for manipulating biological systems. One class of tools includes RNA switches that incorporate RNA-based sensors, known as aptamers. However, most switches reported to-date are responsive to toxic molecules or to endogenous metabolites. F...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: McKeague, Maureen, Wang, Yen-Hsiang, Smolke, Christina D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936389/
https://ncbi.nlm.nih.gov/pubmed/26359915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00518
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