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Design and construction of generalizable RNA-protein hybrid controllers by level-matched genetic signal amplification
For synthetic biology applications, protein-based transcriptional genetic controllers are limited in terms of orthogonality, modularity, and portability. Although ribozyme-based switches can address these issues, their current two-stage architectures and limited dynamic range hinder their broader in...
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Publicado no: | Cell Syst |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5182110/ https://ncbi.nlm.nih.gov/pubmed/27840078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2016.10.008 |
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