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Engineering a microbial platform for de novo biosynthesis of diverse methylxanthines

Engineered microbial biosynthesis of plant natural products can support manufacturing of complex bioactive molecules and enable discovery of non-naturally occurring derivatives. Purine alkaloids, including caffeine (coffee), theophylline (antiasthma drug), theobromine (chocolate), and other methylxa...

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Detalhes bibliográficos
Publicado no:Metab Eng
Main Authors: McKeague, Maureen, Wang, Yen-Hsiang, Cravens, Aaron, Win, Maung Nyan, Smolke, Christina D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5107131/
https://ncbi.nlm.nih.gov/pubmed/27519552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2016.08.003
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