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Kinetic and Equilibrium Binding Characterization of Aptamers to Small Molecules using a Label-Free, Sensitive, and Scalable Platform

[Image: see text] Nucleic acid aptamers function as versatile sensing and targeting agents for analytical, diagnostic, therapeutic, and gene-regulatory applications, but their limited characterization and functional validation have hindered their broader implementation. We report the development of...

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Detalhes bibliográficos
Main Authors: Chang, Andrew L., McKeague, Maureen, Liang, Joe C., Smolke, Christina D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983011/
https://ncbi.nlm.nih.gov/pubmed/24548121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac5001527
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