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Challenges and Opportunities for Small Molecule Aptamer Development
Aptamers are single-stranded oligonucleotides that bind to targets with high affinity and selectivity. Their use as molecular recognition elements has emerged as a viable approach for biosensing, diagnostics, and therapeutics. Despite this potential, relatively few aptamers exist that bind to small...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Hindawi Publishing Corporation
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3488411/ https://ncbi.nlm.nih.gov/pubmed/23150810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/748913 |
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